Make a reservation

Party Size
For 2
Date
Today
Time
7:00 PM
icon/ic_social_proofCreated with Sketch.
Booked 12 times today

Rx Restaurant

4.7
726 reviews
icon/ic_price_rangeCreated with Sketch.
$30 and under
icon/ic_cuisineCreated with Sketch.
Southern
Top Tags:
  • Local Ingredients
  • Creative Cuisine
  • Neighborhood Gem
Located in the Castle Street Art District in Wilmington, NC, Rx Restaurant and Bar is here to serve the best local ingredients around. Our chef is committed to bringing fresh food to your table, so the menu changes daily based on what he can find locally. Parking is free on Castle Street as well as in the parking lot diagonal from us on 5th and Castle!
Dining Style
Casual Dining
icon/ic_cuisineCreated with Sketch.
Cuisines
Southern, Contemporary Southern, Low Country
icon/ic_clockCreated with Sketch.
Hours of operation
Tuesday - Thursday: 5:00pm - 9:00pm, Friday - Saturday: 5:00pm - 9:30pm, Sun: 10:00am- 2:00pm
icon/ic_phoneCreated with Sketch.
Phone number
(910) 399-3080
icon/ic_new_windowCreated with Sketch.
icon/ic_paymentCreated with Sketch.
Payment options
AMEX, Diners Club, Discover, MasterCard, Visa
icon/ic_dress_codeCreated with Sketch.
Dress code
Casual Dress
icon/ic_chefCreated with Sketch.
Executive chef
James Doss
icon/ic_locationCreated with Sketch.
icon/ic_neighborhoodCreated with Sketch.
Neighborhood
icon/ic_cross_streetCreated with Sketch.
Cross street
421 castle st
icon/ic_parking_detailsCreated with Sketch.
Parking details
Parking is free on Castle Street as well as in the large parking lot diagonal from the restaurant!
Additional
Bar Dining, Bar/Lounge, Beer, BYO Wine, Corkage Fee, Full Bar, Non-Smoking, View, Weekend Brunch, Wheelchair Access, Wine
Sort by
Newest
Filters
5.0Dined a day ago

Excellent dinner and service.

Report
Helpful
4.0Dined 3 days ago

Food was great. Good plate presentation. Service was good waiter seemed a bit rushed perhaps overwhelmed (too many tables to attend to) Noise level was high.

Report
Helpful
5.0Dined on June 9, 2018

Rx was outstanding. The drinks were delicious. I had a Lavender Vesper and my spouse had The Cure, a pickle martini type construct. The mood in the restaurant was happy and cozy and our waiter Rick was kind, funny and very knowledgeable. The portions were generous without being too much and we left well fed. All the ingredients were fresh and well made. We will definitly be back!

Report
Helpful
5.0Dined on June 9, 2018

Great service and food! Farm to table. Nice opportunity to enjoy locally grown and made products.

Report
Helpful
5.0Dined on June 9, 2018

Wonderful meal! RX was recommended by a colleague who lives in Wilmington, and we enjoyed a wonderful dinner there. All food is locally sourced. Service is warm and capable, not intrusive but responsive. Our meals were beautifully prepared and delicious! Great place for a celebration -- or just to treat yourself to a great meal!

Report
Helpful
5.0Dined on June 9, 2018

We love RX and consider it one of Wilmington’s best restaurants. The food is consistently good and the staff and servers very accommodating. We can’t wait to go again and see what new items will be featured.

Report
Helpful
5.0Dined on June 7, 2018

I love RX. The food is delicious and the presentation so amazing. I love the variety and freshness of the food. The staff is friendly and attentive. They do not make you feel rushed. The chef is accommodating. An evening at RX is a special occasion whether the reason celebratory or not. A pleasure to dine here.

Report
Helpful
3.0Dined on June 5, 2018

Felt food was ok not enough choices . Service was good. Overpriced for food. Cheese plate was good

Report
Helpful
5.0Dined on June 5, 2018

Great food, Rick was great server as usual!

Report
Helpful
4.0Dined on June 2, 2018

Menu was limited but contained all major categories. Food combinations and flavors were very well matched. Service was excellent. Only drawback is location.

Report
Helpful
5.0Dined on June 1, 2018

Very satisfied. The local food, as advertised, was amazing. It had such a different flavor profile than ordinary restaurants.

Report
Helpful
5.0Dined on May 29, 2018

My family and I simply cannot get enough of the love that the RX puts into every dish they make. Using the finest local produce and suppliers, they are providing some of the best cuisine the city of Wilmington has to offer. Couple this with there amazing& friendly staff you will find yourself wanting to come back to the RX!!

Report
Helpful
5.0Dined on May 26, 2018

My family loves RX. The food is always excellent, the wait staff is knowledgeable and friendly, and the restaurant has a fun vibe.

Report
Helpful
5.0Dined on May 25, 2018

Rx is a Wilmington NC gem. Make sure that you try different plates because you will miss out on some great food if you don't. Get a table full of dishes and enjoy. Servers are friendly and you can choose from great drinks, fine wines and beers. Easy parking makes this a wonderful place to enjoy dinner. Bring your friends and family for a tasty meal. They will make you a custom menu for special events. Love Rx.

Report
Helpful
4.0Dined on May 24, 2018

Located in the old Hall’s Drug Store building on the corner of Castle and 5th Streets, this is the real deal in chef driven, locally sourced, fine dining.

There is nothing snooty about the place although it could put on airs if it wished. No, here you’ll find friendly, helpful waits and a menu featuring the best from this costal community’s farmers and fishermen—and that is a bounty indeed.

A lot of noise is generated by the restaurant’s fried pig’s ears version of Buffalo chicken wings including the blue cheese dressing—but I’d suggest the Crispy Pork Rillettes, (think pork stuffed hush puppies), excellent.

I had Charlotte’s Egg for an entree which is a terrific vegetarian option and shows the chef’s expertise with local vegetables.

The wine list is exceptional. There are 30 or 40 reds and another 30 or 40 whites. Many of the bottles are very reasonably priced ($30). The staff is very helpful in assisting you if you would like—I alway do learn something when I ask a few questions as well as wind up with a perfect wine for dinner. In this case a wonderful pinot gris from Oregon’s Willamette Valley for $40. Delicious.

RX is worth a visit for fine food and wine.

Report
Helpful
5.0Dined on May 19, 2018

This was a return trip to RX for some of us and a first visit for others. As always the food was excellent. Our service tonight was outstanding. We had the heirloom tomatoes and smoked fish spread as appetizers and they were delicious. For entrees our group had NY strip steak, shrimp and grits and two different chicken dishes and all were wonderful. Will definitely be back again.

Report
Helpful
4.0Dined on May 18, 2018

Interesting menu, the food tasted great, and service was good.

Report
Helpful
5.0Dined on May 17, 2018

Wonderful local dining experience!

Report
Helpful
5.0Dined on May 17, 2018

Miguel is an excellent, excellent waiter. Hostess, too. But tables were too close together for our taste; we were not offered a booth (tho we didn't specifically ask), despite small crowd. Generous portions. Was not informed that pigs' ears app and duck entree were spicy. Would recommend highly. Pricey, tho not unreasonable; farm-to-table can add to food cost, I know. Still, we are not in Manhattan.

Report
Helpful
5.0Dined on May 13, 2018

This was a great Sunday brunch for Mother's Day. The food was terrific, fresh and unique. Our service was excellent. This is a "go-to" restaurant with amazing food. Fresh soft-shell crab for me and shrimp and grits for my bride of 39 years.

Report
Helpful
5.0Dined on May 13, 2018

Mother’s Day Brunch

Report
Helpful
5.0Dined on May 13, 2018

We went to Rx for Mother's Day brunch. We were very promptly seated. Our waiter was very attentive and brought us some delicious little biscuits and butter. We had no trouble finding things we wanted to try and were not disappointed. Everything was fresh and delicious. We were too full for dessert, but he brought me a chocolate dipped strawberry for Mother's Day! Will definitely go back.

Report
Helpful
5.0Dined on May 13, 2018

One of our favorite restaurants in Wilmington. The shrimp and grits were excellent with just the right amount of seasoning. The staff is attentive, and made very good recommendations.

Report
Helpful
5.0Dined on May 10, 2018

Great food, quick service

Report
Helpful
5.0Dined on May 5, 2018

Great restaurant. Well worth the price. All food is local and menu changes daily based on the season of meat and vegetables. Will definitely visit again.

Report
Helpful
5.0Dined on May 5, 2018

Wonderful experience. Great food, experienced and professional staff, and great place for any occasion.

Report
Helpful
3.0Dined on May 4, 2018

Skip the pig ears appetizer and ice cream sandwich dessert - left both on the plate. Service rated low because these dishes highly recommended by the waiter. Pork chop cooked perfectly - vegetables great but too much salt spoiled the dish. Ambiance / local ingredients best attributes.

Report
Helpful
5.0Dined on May 4, 2018

I had a friend recommend Rx and I am so happy with the recommendation! The staff was so wonderful and helpful with the menu and everything. I would absolutely recommend this restaurant! I only wish it could be moved closer downtown as it’s a little bit of a hike if you walk rather than drive.

Report
Helpful
5.0Dined on May 1, 2018

Excellent across the board. Look forward to coming back.

Report
Helpful
5.0Dined on April 28, 2018

RX is a favorite spot of ours to frequent for date nights and celebratory dinners and this past visit was no exception. My husband got the Humble Roots Fried Chicken and I had the duck and both were absolutely amazing...oh and make sure do not skip the pig ears. The final treat was a delicious chocolate peanut butter panacotta...just wow! Go and enjoy!

Report
Helpful
4.0Dined on April 21, 2018

Great service, very quiet Saturday evening dinner. Had the fried chicken, sweet potatoes and collards, corn bread and biscuits.

Report
Helpful
5.0Dined on April 19, 2018

Great menu creativity and flavors, they nailed it tonight.

Report
Helpful
5.0Dined on April 18, 2018

RX never dissapoints‼️
Your friends from Old City Barbeque 💙

Report
Helpful
5.0Dined on April 15, 2018

Farm to table experience with very caring staff.

Report
Helpful
5.0Dined on April 12, 2018

I live in Charleston SC--some say the gastronomic center of the South, but Rx certainly would fit in!

Report
Helpful
5.0Dined on April 12, 2018

What a gem ! Loved the neighborhood the restaurant was in . Food was delicious !! Salads were fresh with just right amount of dressing . Duck was very flavorful. Fried chicken was yummy . Good selection of wine.

Report
Helpful
5.0Dined on April 10, 2018

This is a great restaurant. I always enjoy the food and the bar at this place. It can sometimes be a little noisy but not bad. We live about 25 minutes north of the restaurant area so this is a trip for us but we do it several times a year. I always recommend this spot to people staying downtown.

Report
Helpful
5.0Dined on April 7, 2018

We were a group of four going for dinner and theater. The staff were very friendly, knowledgeable and accommodating to our timing needs for the theater. The menu is a Day by Day affair, with very interesting local items, all of which looked delicious. Two of us had the shrimp and grits and the other two had two different types of chicken. All were quite good and ample, with local sides. I would highly recommend this restaurant for a great evening meal.

Report
Helpful
5.0Dined on April 1, 2018

We had an excellent experience at RX on Easter. Our server was fantastic and the food was AMAZING. Seriously, this place is GEM. Highly recommend!

Report
Helpful
5.0Dined on April 1, 2018

Food was incredible & Rick was an awesome server. He made a great experience fantastic. Want to try a few of the specialty cocktails next time. Will arrive earlier. (8:30 res).

Report
Helpful
1
2
3
19